I believe BGOL has brothers with abundant knowledge and i'm sure they will share more info on this.
It Killed J Dilla, MJ had it, and others
How bad is this to a 22 year old girl who has whole life ahead of her?
What's the best or worst case scenario if she gets married?
http://en.wikipedia.org/wiki/Systemic_lupus_erythematosus
It Killed J Dilla, MJ had it, and others
How bad is this to a 22 year old girl who has whole life ahead of her?
What's the best or worst case scenario if she gets married?

Systemic lupus erythematosus (i/sɪˈstɛmɪk ˈluːpəs ˌɛrɪθiːməˈtoʊsəs/), often abbreviated to SLE or lupus, is a systemic autoimmune disease (or autoimmune connective tissue disease) that can affect any part of the body. As occurs in other autoimmune diseases, the immune system attacks the body's cells and tissue, resulting in inflammation and tissue damage.[1] It is a Type III hypersensitivity reaction caused by antibody-immune complex formation.
SLE most often harms the heart, joints, skin, lungs, blood vessels, liver, kidneys, and nervous system. The course of the disease is unpredictable, with periods of illness (called flares) alternating with remissions. The disease occurs nine times more often in women than in men, especially in women in child-bearing years ages 15 to 35, and is also more common in those of non-European descent.[2][3][4]
http://en.wikipedia.org/wiki/Systemic_lupus_erythematosus