The African slave who taught America how to vaccinate itself from smallpox
Onesimus Spreads Wisdom That Saves Lives of Bostonians During a Smallpox Epidemic
https://www.historyofvaccines.org/content/blog/onesimus-smallpox-boston-cotton-mather
February 3, 2019 Rene F. Najera
In the early 1700s, about a century before Edward Jenner conceived the idea of a smallpox vaccine based on the cowpox virus, smallpox was going through New England and other American Colonies. In Massachusetts, colonists there saw smallpox arrive with cargo ships to Boston over and over again. There was not much the authorities could do beyond imposing quarantines and treating the sick.
This changed in 1721 thanks to the wisdom passed on from Onesimus, an African slave sold to Cotton Mather, an influential minister in Boston. (You might remember Mather from learning about the Salem Witch Trials.) Mather had bought Onesimus in 1706 and came to converse with him and learn about Onesimus' past. When Mather asked Onesimus if he had ever had smallpox back in Africa, Onesimus described the practice of variolation to prevent smallpox epidemics.
Variolation consisted of first taking infectious material (like pus) from the blisters of smallpox patients. A healthy person then receives the material through a cut in the skin in a controlled manner and under the supervision of a physician. This was done so that the smallpox symptoms would be milder but still confer some sort of immunity in the future. Of course, the procedure was not without risk. People still developed severe symptoms and even died from smallpox via variolation, but those who died were in much smaller proportion to those who acquired it naturally from another person. (See how Benjamin Franklin reasoned it through and put his observations in a pamphlet: https://www.historyofvaccines.org/content/blog/epidemiologist-benjamin-franklin).
After hearing Onesimus' story, Cotton Mather began to research the practice of variolation. He found that it was practiced in many parts of the world, not just Africa. Or, as he recorded in his diary, "the new Method used by the Africans and Asiaticks, to prevent and abate the Dangers of the Small-Pox, and infallibly to save the Lives of those that have it wisely managed upon them." Places like China and Turkey had their own versions of variolation based on the same principle of exposing a person under controlled circumstances rather allowing them to contract it naturally. The practice was so effective in conferring immunity that African slaves sold in Massachusetts at the time were deemed to be more valuable if they bore the scar of variolation.
This research and correspondence with medical experts at the time encouraged Cotton Mather to push for variolation in the colonies. He burned some of his political and social capital in advocating for variolation before the next epidemic hit Boston. Needless to say, his proposal met with resistance. Anti-variolation sentiment was strong in its response to the idea:
the original anti-vaxxers !^^
www.history.com
https://www.history.com/news/smallpox-vaccine-onesimus-slave-cotton-mather
How an African Slave in Boston Helped Save Generations from Smallpox
In the early 1700s, Onesimus shared a revolutionary way to prevent smallpox
he news was terrifying to colonists in Massachusetts: Smallpox had made it to Boston and was spreading rapidly. The first victims, passengers on a ship from the Caribbean, were shut up in a house identified only by a red flag that read “God have mercy on this house.” Meanwhile, hundreds of residents of the bustling colonial town had started to flee for their lives, terrified of what might happen if they exposed themselves to the frequently deadly disease.
They had reason to fear. The virus was extremely contagious, spreading like wildfire in large epidemics. Smallpox patients experienced fever, fatigue and a crusty rash that could leave disfiguring scars. In up to 30 percent of cases, it killed.
A Boston advertisement for a cargo of about 250 slaves recently arrived from Africa circa 1700, particularly stressing that the slaves are free of smallpox, having been quarantined on their ship.
MPI/Getty Images
But the smallpox epidemic of 1721 was different than any that came before it. As sickness swept through the city, killing hundreds in a time before modern medical treatment or a robust understanding of infectious disease, an enslaved man known only as Onesimus suggested a potential way to keep people from getting sick. Intrigued by Onesimus’ idea, a brave doctor and an outspoken minister undertook a bold experiment to try to stop smallpox in its tracks.
Smallpox was one of the era’s deadliest afflictions. “Few diseases at this time were as universal or fatal,” notes historian Susan Pryor. The colonists saw its effects not just among their own countrymen, but among the Native Americans to whom they introduced the disease. Smallpox destroyed Native communities that, with no immunity, were unable to fight off the virus.
Smallpox also entered the colonies on slave ships, transmitted by enslaved people who, in packed and unsanitary quarters, passed the disease along to one another and, eventually, to colonists at their destinations. One of those destinations was Massachusetts, which was a center of the early slave trade. The first slaves had arrived in Massachusetts in 1638, and by 1700, about 1,000 slaves lived in the colony, most in Boston.
In 1706, an enslaved West African man was purchased for the prominent Puritan minister Cotton Mather by his congregation. Mather gave him the name Onesimus, after a Biblical slave whose name meant “useful.” Mather, who had been a powerful figure in the Salem Witch Trials, believed that slave owners had a duty to convert slaves to Christianity and educate them. But like other white men of his era, he also looked down on what he called the “Devilish rites” of Africans and worried that enslaved people might openly rebel.
Mather didn’t trust Onesimus: He wrote about having to watch him carefully due to what he thought was “thievish” behavior, and recorded in his diary that he was “wicked” and “useless.” But in 1716, Onesimus told him something he did believe: That he knew how to prevent smallpox.
Onesimus, who “is a pretty intelligent fellow,” Mather wrote, told him he had had smallpox—and then hadn’t. Onesimus said that he “had undergone an operation, which had given him something of the smallpox and would forever preserve him from it...and whoever had the courage to use it was forever free of the fear of contagion.”
The operation Onesimus referred to consisted of rubbing pus from an infected person into an open wound on the arm. Once the infected material was introduced into the body, the person who underwent the procedure was inoculated against smallpox. It wasn’t a vaccination, which involves exposure to a less dangerous virus to provoke immunity. But it did activate the recipient’s immune response and protected against the disease most of the time.
Mather was fascinated. He verified Onesimus’ story with that of other enslaved people, and learned that the practice had been used in Turkey and China. He became an evangelist for inoculation—also known as variolation—and spread the word throughout Massachusetts and elsewhere in the hopes it would help prevent smallpox.
Cotton Mather.
Corbis/Getty Images
But Mather hadn’t bargained on how unpopular the idea would be. The same prejudices that caused him to distrust his servant made other white colonists reluctant to undergo a medical procedure developed by or for black people. Mather “was vilified,” historian Ted Widmer told WGBH. “A local newspaper, called The New England Courant, ridiculed him. An explosive device was thrown through his windows with an angry note. There was an ugly racial element to the anger.” Religion also contributed: Other preachers argued that it was against God’s will to expose his creatures to dangerous diseases.
(some things aint changed i see
)
But in 1721, Mather and Zabdiel Boylston, the only physician in Boston who supported the technique, got their chance to test the power of inoculation. That year, a smallpox epidemic spread from a ship to the population of Boston, sickening about half of the city’s residents. Boylston sprang into action, inoculating his son and his slaves against the disease. Then, he began inoculating other Bostonians. Of the 242 people he inoculated, only six died—one in 40, as opposed to one in seven deaths among the population of Boston who didn’t undergo the procedure.
The smallpox epidemic wiped out 844 people in Boston, over 14 percent of the population. But it had yielded hope for future epidemics. It also helped set the stage for vaccination. In 1796, Edward Jenner developed an effective vaccine that used cowpox to provoke smallpox immunity. It worked. Eventually, smallpox vaccination became mandatory in Massachusetts.
Did Onesimus live to see the success of the technique he introduced to Mather? It isn’t clear. Nothing is known of his later life other than that he partially purchased his freedom. To do so, writes historian Steven J. Niven, he gave Mather money to purchase another slave. What is clear is that the knowledge he passed on saved hundreds of lives—and led to the eventual eradication of smallpox.
In 1980, the World Health Organization declared smallpox entirely eradicated due to the spread of immunization worldwide. It remains the only infectious disease to have been entirely wiped out.
================
resources
=====
https://qz.com/africa/1854780/an-african-slave-taught-america-to-vaccinate-from-smallpox/

https://undark.org/2020/04/02/slave-smallpox-onesimus/
https://historydaily.org/onesimus-smallpox-inoculation
“I didn't know I was a slave until I found out I couldn’t do the things I wanted.” — Frederick Douglass
While some may never tire of hearing about the greatness of Civil Rights leaders, famous Black athletes and renowned entertainers, Black History Month also represents a time to focus on the unsung.
In an email,
Laurie Endicott Thomas, the author of “No More Measles: The Truth About Vaccines and Your Health,” said the most important person in the history of American medicine was an enslaved African whose real name we do not know.
“His slave name was Onesimus, which means useful in Latin. The Biblical Onesmius ran away from slavery but was persuaded to return to his master,” Thomas said. “The African-American Onesimus was the person who introduced the practice of immunization against smallpox to North America. This immunization process was called variolation because it involved real smallpox. Variolation led to sharp decreases in the death rate from smallpox and an important decrease in overall death rates,” she said.
Onesimus Spreads Wisdom That Saves Lives of Bostonians During a Smallpox Epidemic
https://www.historyofvaccines.org/content/blog/onesimus-smallpox-boston-cotton-mather
February 3, 2019 Rene F. Najera
In the early 1700s, about a century before Edward Jenner conceived the idea of a smallpox vaccine based on the cowpox virus, smallpox was going through New England and other American Colonies. In Massachusetts, colonists there saw smallpox arrive with cargo ships to Boston over and over again. There was not much the authorities could do beyond imposing quarantines and treating the sick.
This changed in 1721 thanks to the wisdom passed on from Onesimus, an African slave sold to Cotton Mather, an influential minister in Boston. (You might remember Mather from learning about the Salem Witch Trials.) Mather had bought Onesimus in 1706 and came to converse with him and learn about Onesimus' past. When Mather asked Onesimus if he had ever had smallpox back in Africa, Onesimus described the practice of variolation to prevent smallpox epidemics.
Variolation consisted of first taking infectious material (like pus) from the blisters of smallpox patients. A healthy person then receives the material through a cut in the skin in a controlled manner and under the supervision of a physician. This was done so that the smallpox symptoms would be milder but still confer some sort of immunity in the future. Of course, the procedure was not without risk. People still developed severe symptoms and even died from smallpox via variolation, but those who died were in much smaller proportion to those who acquired it naturally from another person. (See how Benjamin Franklin reasoned it through and put his observations in a pamphlet: https://www.historyofvaccines.org/content/blog/epidemiologist-benjamin-franklin).
After hearing Onesimus' story, Cotton Mather began to research the practice of variolation. He found that it was practiced in many parts of the world, not just Africa. Or, as he recorded in his diary, "the new Method used by the Africans and Asiaticks, to prevent and abate the Dangers of the Small-Pox, and infallibly to save the Lives of those that have it wisely managed upon them." Places like China and Turkey had their own versions of variolation based on the same principle of exposing a person under controlled circumstances rather allowing them to contract it naturally. The practice was so effective in conferring immunity that African slaves sold in Massachusetts at the time were deemed to be more valuable if they bore the scar of variolation.
This research and correspondence with medical experts at the time encouraged Cotton Mather to push for variolation in the colonies. He burned some of his political and social capital in advocating for variolation before the next epidemic hit Boston. Needless to say, his proposal met with resistance. Anti-variolation sentiment was strong in its response to the idea:
the original anti-vaxxers !^^


How an Enslaved African Man in Boston Helped Save Generations from Smallpox | HISTORY
In the early 1700s, Onesimus shared a revolutionary way to prevent smallpox.
How an African Slave in Boston Helped Save Generations from Smallpox
In the early 1700s, Onesimus shared a revolutionary way to prevent smallpox

he news was terrifying to colonists in Massachusetts: Smallpox had made it to Boston and was spreading rapidly. The first victims, passengers on a ship from the Caribbean, were shut up in a house identified only by a red flag that read “God have mercy on this house.” Meanwhile, hundreds of residents of the bustling colonial town had started to flee for their lives, terrified of what might happen if they exposed themselves to the frequently deadly disease.
They had reason to fear. The virus was extremely contagious, spreading like wildfire in large epidemics. Smallpox patients experienced fever, fatigue and a crusty rash that could leave disfiguring scars. In up to 30 percent of cases, it killed.
A Boston advertisement for a cargo of about 250 slaves recently arrived from Africa circa 1700, particularly stressing that the slaves are free of smallpox, having been quarantined on their ship.
MPI/Getty Images
But the smallpox epidemic of 1721 was different than any that came before it. As sickness swept through the city, killing hundreds in a time before modern medical treatment or a robust understanding of infectious disease, an enslaved man known only as Onesimus suggested a potential way to keep people from getting sick. Intrigued by Onesimus’ idea, a brave doctor and an outspoken minister undertook a bold experiment to try to stop smallpox in its tracks.
Smallpox was one of the era’s deadliest afflictions. “Few diseases at this time were as universal or fatal,” notes historian Susan Pryor. The colonists saw its effects not just among their own countrymen, but among the Native Americans to whom they introduced the disease. Smallpox destroyed Native communities that, with no immunity, were unable to fight off the virus.
Smallpox also entered the colonies on slave ships, transmitted by enslaved people who, in packed and unsanitary quarters, passed the disease along to one another and, eventually, to colonists at their destinations. One of those destinations was Massachusetts, which was a center of the early slave trade. The first slaves had arrived in Massachusetts in 1638, and by 1700, about 1,000 slaves lived in the colony, most in Boston.
In 1706, an enslaved West African man was purchased for the prominent Puritan minister Cotton Mather by his congregation. Mather gave him the name Onesimus, after a Biblical slave whose name meant “useful.” Mather, who had been a powerful figure in the Salem Witch Trials, believed that slave owners had a duty to convert slaves to Christianity and educate them. But like other white men of his era, he also looked down on what he called the “Devilish rites” of Africans and worried that enslaved people might openly rebel.
Mather didn’t trust Onesimus: He wrote about having to watch him carefully due to what he thought was “thievish” behavior, and recorded in his diary that he was “wicked” and “useless.” But in 1716, Onesimus told him something he did believe: That he knew how to prevent smallpox.
Onesimus, who “is a pretty intelligent fellow,” Mather wrote, told him he had had smallpox—and then hadn’t. Onesimus said that he “had undergone an operation, which had given him something of the smallpox and would forever preserve him from it...and whoever had the courage to use it was forever free of the fear of contagion.”
The operation Onesimus referred to consisted of rubbing pus from an infected person into an open wound on the arm. Once the infected material was introduced into the body, the person who underwent the procedure was inoculated against smallpox. It wasn’t a vaccination, which involves exposure to a less dangerous virus to provoke immunity. But it did activate the recipient’s immune response and protected against the disease most of the time.
Mather was fascinated. He verified Onesimus’ story with that of other enslaved people, and learned that the practice had been used in Turkey and China. He became an evangelist for inoculation—also known as variolation—and spread the word throughout Massachusetts and elsewhere in the hopes it would help prevent smallpox.
Cotton Mather.
Corbis/Getty Images
But Mather hadn’t bargained on how unpopular the idea would be. The same prejudices that caused him to distrust his servant made other white colonists reluctant to undergo a medical procedure developed by or for black people. Mather “was vilified,” historian Ted Widmer told WGBH. “A local newspaper, called The New England Courant, ridiculed him. An explosive device was thrown through his windows with an angry note. There was an ugly racial element to the anger.” Religion also contributed: Other preachers argued that it was against God’s will to expose his creatures to dangerous diseases.
(some things aint changed i see

But in 1721, Mather and Zabdiel Boylston, the only physician in Boston who supported the technique, got their chance to test the power of inoculation. That year, a smallpox epidemic spread from a ship to the population of Boston, sickening about half of the city’s residents. Boylston sprang into action, inoculating his son and his slaves against the disease. Then, he began inoculating other Bostonians. Of the 242 people he inoculated, only six died—one in 40, as opposed to one in seven deaths among the population of Boston who didn’t undergo the procedure.
The smallpox epidemic wiped out 844 people in Boston, over 14 percent of the population. But it had yielded hope for future epidemics. It also helped set the stage for vaccination. In 1796, Edward Jenner developed an effective vaccine that used cowpox to provoke smallpox immunity. It worked. Eventually, smallpox vaccination became mandatory in Massachusetts.
Did Onesimus live to see the success of the technique he introduced to Mather? It isn’t clear. Nothing is known of his later life other than that he partially purchased his freedom. To do so, writes historian Steven J. Niven, he gave Mather money to purchase another slave. What is clear is that the knowledge he passed on saved hundreds of lives—and led to the eventual eradication of smallpox.
In 1980, the World Health Organization declared smallpox entirely eradicated due to the spread of immunization worldwide. It remains the only infectious disease to have been entirely wiped out.
================
resources
=====
https://qz.com/africa/1854780/an-african-slave-taught-america-to-vaccinate-from-smallpox/

https://undark.org/2020/04/02/slave-smallpox-onesimus/
https://historydaily.org/onesimus-smallpox-inoculation
“I didn't know I was a slave until I found out I couldn’t do the things I wanted.” — Frederick Douglass
While some may never tire of hearing about the greatness of Civil Rights leaders, famous Black athletes and renowned entertainers, Black History Month also represents a time to focus on the unsung.
In an email,
Laurie Endicott Thomas, the author of “No More Measles: The Truth About Vaccines and Your Health,” said the most important person in the history of American medicine was an enslaved African whose real name we do not know.
“His slave name was Onesimus, which means useful in Latin. The Biblical Onesmius ran away from slavery but was persuaded to return to his master,” Thomas said. “The African-American Onesimus was the person who introduced the practice of immunization against smallpox to North America. This immunization process was called variolation because it involved real smallpox. Variolation led to sharp decreases in the death rate from smallpox and an important decrease in overall death rates,” she said.