Best wishes to her health-wise.
Never met my mom's parents. Both passed long before I was born. She (my mom) lost her mother when she was only 8yo. Her mom was 38 at the time & had battled Lupus for some time.
https://en.wikipedia.org/wiki/Systemic_lupus_erythematosus
Systemic lupus erythematosus, often abbreviated as
SLE or
lupus, is a
systemic autoimmune disease (or
autoimmune connective tissue disease) in which the body’s
immune system mistakenly attacks healthy tissue. There are many kinds of
lupus. The most common type is systemic lupus erythematosus (SLE), which affects many internal organs in the body. SLE most often harms the
heart,
joints,
skin,
lungs,
blood vessels,
liver,
kidneys, and
nervous system. The course of the disease is unpredictable, with periods of illness (called
flare-ups) alternating with
remissions.
The cause is believed to be an environmental trigger, which results in a misdirected immune response in people who are genetically susceptible. A normal immune system makes proteins called
antibodies that protect against pathogens such as viruses and bacteria. Lupus is characterized by the presence of
antibodies against a person's own proteins; these are most commonly
anti-nuclear antibodies, which are found in nearly all cases. These antibodies lead to
inflammation.
[1][2]
There is no cure for SLE. It is mainly treated with
immunosuppressants such as
cyclophosphamide and
corticosteroids, the goal of which is to keep symptoms under control. SLE can be fatal. The leading cause of death is from cardiovascular disease due to accelerated
atherosclerosis. Life expectancy has improved over the decades. The 10-year survival rate is 92–95% and is close to that of people without lupus. This is due in part to better treatments, but also to identification of milder cases.
[1][3]
Global rates of disease varies from 20 to 70 per 100,000. The disease occurs nine times more often in women than in men, especially in women of child-bearing years (ages 15 to 35). It is also more common in those of
African-American or
Caribbean descent.
[1][4][5] Rates of disease in the developing world are unclear.
[6] Childhood systemic lupus erythematosus generally presents between the ages of 3 and 15, with girls outnumbering boys 4:1, and typical skin manifestations being a
butterfly-shaped rash on the face, and
photosensitivity.
[7] Lupus is Latin for wolf. In the 18th century, when lupus was just starting to be recognized as a disease, it was thought that it was caused by a wolf's bite.
[8] This may have been because of the distinctive
malar rash characteristic of lupus. (Once full-blown, the round, disk-shaped rashes heal from the inside out, leaving a bite-like imprint.)