They boast a combined 61 knockout victories with only seven of their wins having taken them the distance. They have lost a total of five fights out of 68, with one of the fighters being undefeated over the course of 29 of them.
On Saturday night, they will be matched in a Showtime televised bout as 35-year-old former world champion, Rafael Marquez of Mexico City challenges 27-year-old, Puerto Rican southpaw WBO featherweight (126 pounds) king Juan Manuel Lopez in a Top Rank Promotions clash of hard-hitting Latino fighters at The MGM Grand in Las Vegas.
Lopez is making the second defense of his crown against Marquez, whose promoter is Gary Shaw, in yet another battle in the long-running rivalry between Mexican boxers and those from Puerto Rico.
FanHouse sought the opinions of 10 boxing experts, only one of whom believes that their clash will last the 12-round distance.
Bob Canobbio, CompuBox, Inc.
Juan Manuel Lopez W 12 Rafael Marquez: Juan Manuel Lopez should win. He's younger, stronger and quicker. Rafael Marquez has a puncher's chance though, as opponents have landed 37 percent of their power shots against Lopez.
My pick is Lopez by decision, but Marquez will have his moments.
Steve Farhood, Showtime boxing analyst
Juan Manuel Lopez by KO over Rafael Marquez: It's tough not to pick Juan Manuel Lopez, even though this is the sternest test of his career.
Rafael Marquez is relatively new to 126 pounds, and while he looked good in his fourth fight with Israel Vazquez, that series had to take something out of him.
With that said, Lopez has shown signs of vulnerability, particularly against Rogers Mtagwa and Bernabe Concepcion. Look for a shootout, with Lopez wearing down Marquez and winning by stoppage.
Norm Frauenheim, 15rounds.com
Juan Manuel Lopez by late-round stoppage over Rafael Marquez: Fight of the Year potential is there because a convincing case can be made for and against both Rafael Marquez and Juan Manuel Lopez. There is Juanma's youth and offensive arsenal.
There is Marquez' tactical skill, complemented by a counter-punch that can make a young star look old. But those evident strengths are offset by reasons to wonder about them and their chances.
In a surprising struggle that proved to be Juanma's toughest fight thus far, the 27-year-old Puerto Rican featherweight often appeared baffled and unable to adjust against Rogers Mtagwa, who possesses only a fraction of Marquez' skill and instinct.
Then, there is time, wear, tear and Israel Vazquez. All could have turned the 35-year-old Marquez into a shell of the pound-for-pound contender he once was. It looked as if there might be a lot left last May in Marquez's third-round knockout of Vazquez at Los Angeles' Staples Center.
Even that, however, is undercut by doubt about whether Vazquez already had been pushed past his peak and toward retirement. Marquez is at the crossroads. Then again, so is Juanma, whose next step up the ladder of the boxing marquee depends he can get past the veteran from Mexico City.
The pick here is that Juanma will do exactly that with some newfound smarts to go along with all that offensive dynamite for a late-round stoppage of Marquez.
Kevin Iole, Yahoo! Sports
Juan Manuel Lopez TKO 10 Rafael Marquez: Juan Manuel Lopez is one of the game's rising stars and will prove it in this classic young star versus veteran star fight. Lopez is an extraordinarily hard puncher and a gifted boxer.
Rafael Marquez is as tough as they come. But Marquez's win in May over a badly faded Israel Vazquez is little more than a mirage.
This time, Marquez is in with a bigger, stronger, faster guy who is a hard hitter and extremely hungry. I expect a brilliant performance by Juanma and a stoppage as they move down the stretch.
Steve Kim, MaxBoxing.com
Juan Manuel Lopez TKO 6 Rafael Marquez: I think Lopez is the younger, fresher fighter, with better legs and reflexes.
I like him to win by mid-round stoppage in an entertaining slugfest.
Robert Morales, Los Angeles Daily News/Long Beach Press Telegram
Juan Manuel Lopes by late-round stoppage over Rafael Marquez: I believe that Juan Manuel Lopez will stop Rafael Marquez in the second half of the fight.
Marquez is still a good fighter, but the much younger Lopez is at the top of his game and will be too much for Marquez. This should be a slugfest as both fighters are terrific knockout artists.
Kieran Mulvaney, ESPN Boxing and Reuters
Juan Manuel Lopez W 12 Rafael Marquez: There was a time when I thought Juan Manuel Lopez had real major star potential.
Then there was a period, following his fights against Gerry Penalosa, Olivier Lontchi, and Rogers Mtagwa, when I thought he was stagnating.
Moving up four pounds seems to have reinvigorated him though. Stopping Steven Luevano was very impressive, and his brief brawl with Bernabe Concepcion was the stuff that stars are made of. He's up against a sure-fire, first-ballot Hall of Famer on Saturday night, though.
Rafael Marquez also looked reinvigorated after rebounding from those tough losses to Israel Vazquez. Lopez isn't going to be able to blast through Marquez the way he did to Concepcion, and he isn't going to be able to dominate and break him down the way he did against Luevano.
I do, however, think that the bigger, younger man, with substantially less ring wear on him, will overcome a few moments when Marquez troubles him with some tricks he hasn't seen before.
Eventually, Lopez's constant pressure will see him pull ahead in the final third, possibly by late stoppage. But I think that, in the end, it's going to be a clear decision win for Lopez.
Lance Pugmire, The Los Angeles Times
Juan Manuel Lopez KO 8 Rafael Marquez: I like Juan Manuel Lopez to win by eighth-round stoppage. Rafael Marquez has proven himself to be a warrior in the four Israel Vazquez fights.
But Marquez is now stepping in against a young champion ascending to his peak, and I believe Lopez's energy and power will decide the bout despite credible opinions that Marquez retains enough skill and guile to topple his younger foe.
Joe Santoliquito, Managing Editor Ring Magazine
Rafael Marquez KO 11 Juan Manuel Lopez: I still think Rafael Marquez has something left in the tank, and that his wars with Israel Vazquez didn't completely zap him of everything.
Juan Manuel Lopez has a questionable chin, and it's certainly going to be tested here. This could be a Fight of the Year candidate.
Michael David Smith, FanHouse.com
Juan Manuel Lopez TKO 7 Rafael Marquez: Juan Manuel Lopez said last week that he actually hopes to have a long fight with Rafael Marquez rather than win with a quick knockout.
I think Marquez can last a few rounds with Lopez, but ultimately Lopez will just be too much for him. Lopez by seventh-round TKO.
The experts have spoken by a margin of 9-to-1 that Juan Manuel Lopez will defeat Rafael Marquez.
So BGOL experts, what's your take on this fight?