Cannabis??: What is delta-8?,What is delta-10?, What is THC-O?

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What is delta-8?






Delta-8 is a cannabis compound that has become popular because of its similarity to delta-9 THC, the main compound in cannabis that gets you high, causing euphoria, happiness, sedation, symptom relief, and much more. Large amounts of THC are found in a majority of cannabis strains.


The similarities between the two cannabinoids lie in their chemical structures and their names. THC’s scientific name is delta-9-tetrahydrocannabinol, or delta-9 THC, or just delta-9. Delta-8 is short for delta-8-tetrahydrocannabinol, or delta-8 THC. Delta-8 THC can cause effects similar to regular delta-9 THC—but they will be much less potent.

Delta-8 and delta-9 are both forms of THC. In common usage, when people refer to THC they are talking about delta-9 THC. (In this article, when we use the term “THC” without a modifier, we are referring to delta-9 THC.)

Currently, the legality of delta-8 is hazy. It can be extracted from either hemp or cannabis. Because of the 2018 farm bill, hemp can be legally grown and used for extractions all over the United States, making delta-8 legal in states where delta-9 THC is illegal—sometimes.

Nearly all delta-8 THC on the market today is manufactured from hemp-derived CBD, which makes it, in theory at least, part of a federally legal chain of origin.

People in states where THC is illegal crave cannabis products and are now looking to delta-8 because it may be legal in their state, even though it is less potent than regular THC. Many hemp-based extractors are ramping up delta-8 production to meet this new demand and shipping it all over the US.


Delta-8 vs. delta-9 THC: What’s the difference?

Delta-8, like delta-9 (regular THC), binds to the body’s endocannabinoid system, which causes you to feel high. Chemically, delta-8 and delta-9 are similar in that they both have a double bond in their structures. This double bond is thought to produce the intoxicating effects that make you feel high.

The two THCs are chemically different in the placement of the double bond. Both cannabinoids have a chain of carbon atoms, but delta-8 has the double bond on the eighth carbon, whereas delta-9 has it on the ninth.

Delta-8 binds to the endocannabinoid system in a slightly different fashion because of the location of its double bond. This is what is thought to make delta-8 much less potent than regular THC. However, more research needs to be done on delta-8 and how it interacts with the body.


Will delta-8 get you high?

Delta-8 will get you high, albeit not as high as common delta-9 THC. For those living in states where cannabis is illegal, delta-8 may be a legal way to experience some THC-like effects from cannabis.


Some consumers may even prefer cannabis products that aren’t as strong as common THC, even if they can legally obtain THC products. THC can cause negative effects for some, bringing on anxiety or paranoia. Delta-8 may offer a smoother, milder high.

Leafly’s Dante Jordan tried delta-8 THC and described it as a lighter, more energizing high than traditional delta-9 THC. “Yes, delta-8 definitely gets you high,” he wrote, “but it was a lighter high than I’m accustomed to from smoking joints, taking dabs, and eating regular edibles.”


Effects of delta-8

Delta-8 consumers report many of the same effects as THC, such as mild euphoria, happiness, uplifting feelings, and relief from some symptoms such as pain, although the compound is much less potent. Delta-8 can also help with insomnia.

Side effects may be similar to those of THC, including dry mouth, red eyes, getting the munchies, short-term memory, paranoia, or anxiety. It’s important to note that delta-8 hasn’t been studied extensively and more research is needed on the effects it has on the mind and body.

Delta-8 vs. CBD
Delta-8 has more similarities to THC (delta-9) than CBD, both in its chemical structure and because it gets you high. Delta-8 THC binds to the body’s endocannabinoid system more like delta-9 THC. CBD doesn’t bind as readily to the endocannabinoid system, making it non-intoxicating, although CBD can offer medicinal benefits for the consumer.

If you are looking for effects similar to THC but with a reduced potency, delta-8 may be for you. If you seek relief from certain symptoms and don’t want to get intoxicated, you may want to try a CBD product.


How to dose delta-8

For most people, especially moderate or experienced consumers, delta-8 will feel much weaker than regular THC. If you are new to cannabis, delta-8 could affect you strongly—it depends on your body chemistry.


To give a sense of delta-8’s potency relative to THC, delta-8 edible producers commonly measure and dose their gummies at more than twice the strength of THC gummies:

  • THC gummies often come in 10mg gummies—people may take half a gummy or a full gummy for a dose, either 5mg or a full 10mg.
  • Delta-8 gummies often come in 25mg gummies—so half of one would be 12.5mg, and a full gummy is 25mg.
In creating these standard gummies, producers are calculating that delta-8 is less than half as strong as regular THC, so a 25mg delta-8 gummy might equate to the effects of a 10mg THC gummy.

Again, it’s important to note that very little research has been done on delta-8. We don’t know much about how strong its effects are, and how it affects the body. As with any cannabis product, the chemical profile of the cannabis, your body’s chemistry, your tolerance level, your set and setting, and the amount you take all affect how you will feel.

It’s always recommended to take a little bit at first and then wait for the onset of effects before taking more. The consumption method will affect how quickly you feel those effects. If you’re vaping delta-8, you should feel the effects within ten minutes or less; if taking edibles, wait at least an hour or two before taking more.


Is delta-8 legal?

Delta-8 currently exists in a legal gray area.

Few state laws specifically address delta-8 THC at this time. Most state laws that pertain to marijuana or cannabis use language that covers marijuana, cannabis, THC, CBD, or delta-9 tetrahydrocannabinol. There are 11 states where delta-8 is believed to be illegal according to state law. (See list below, under “Can I get delta-8 in the mail?”)

The federal Drug Enforcement Administration (DEA) has, in a proposed rule, indirectly classified delta-8 THC as a Schedule I controlled substance, which would make it federally illegal. That rule is not yet final.

Delta-8 THC is commonly sourced from hemp, not cannabis, which is why it’s currently sold in many states where cannabis is illegal. To be more specific, nearly all delta-8 THC currently on the market is derived from CBD extracted from federally legal hemp.

This can be a little confusing because hemp is, technically, a cannabis plant that contains less than 0.3% THC. When we talk about “cannabis,” though, we’re commonly referring to cannabis plants with THC content of 0.3% or higher.



The 2018 farm bill, a federal act passed by Congress, legalized hemp in the United States. That act defines hemp as: “All derivatives, extracts, cannabinoids, isomers, acids, salts, and salts of isomers, whether growing or not, with a delta-9 tetrahydrocannabinol concentration of not more than 0.3 percent.” This language makes delta-8 legal, because it does not contain any delta-9 THC.

However, some states have chosen not to adopt this specific language of the farm bill in their own state laws, making delta-8 illegal in certain states. Producers and retailers of delta-8 sell only to states that have laws mirroring the farm bill’s language. Even then, some producers may only sell to certain states based on their own interpretation of a state’s laws.


Additionally, in August 2020, the DEA released an Interim Final Rule (IFR), a document meant to update and confirm the differences between hemp and cannabis. That interim rule said: “All synthetically derived tetrahydrocannabinols remain Schedule I controlled substances,” which would make delta-8 illegal because it is a tetrahydrocannabinol that is extracted, or synthetically derived.

So whether the farm bill’s language stands, which outlaws plants with more than 0.3% delta-9 THC, or the new IFR language is adopted, which bans all tetrahydrocannabinols, will determine the fate of delta-8. The DEA’s IFR is open for review until October 2021, and until then, delta-8’s federal legality remains hazy.

Is delta-8 safe?
Leafly correspondent Marissa Wenzke investigated the safety factor of delta-8 THC products. The experts she consulted suggested the main risk factor could come from untested, unlicensed delta-8 THC vape cartridges purchased on the unregulated market.

In 2019, the booming market in illicit-market THC vape cartridges allowed bad actors to pollute their vape oil with toxic vitamin E acetate, which led to thousands of hospitalizations and more than 60 deaths. Today’s delta-8 THC cartridges, when purchased outside a legal state-licensed cannabis store, hold the same risks.



Can I get delta-8 in the mail?
You can receive delta-8 in the mail depending on which state you live in. Delta-8 isn’t legal in all states, and different producers may choose not to ship to certain states because of its hazy legality. Be sure to check a producer’s website to see if they ship to your state. Surprisingly, states that have legal, adult-use cannabis laws don’t always allow delta-8.

Commonly, producers will ship delta-8 to all states except these:

  • Alaska
  • Arizona
  • Colorado
  • Delaware
  • Idaho
  • Iowa
  • Mississippi
  • Montana
  • Rhode Island
  • Utah
How is delta-8 made?
Delta-8 is found in trace amounts in cannabis and hemp plants, and as hemp is legal to grow anywhere in the US and more readily available, the cannabinoid is often sourced from that.

Commonly, CBD is extracted from hemp and refined into an isolate, and then CBD isolate is synthesized into delta-8. As such, delta-8 requires more processing and is more expensive to make than CBD, but this increased production cost is balanced out by the high demand for it.

How to find good, safe delta-8
As delta-8 is relatively new to the market, it may be challenging to find products that are what they say they are and actually contain delta-8. When shopping for delta-8 products, check out a producer’s website to see if they have information on how they source and create their products.

Quality, tested products usually have a QR code or batch number on the box that allows you to look up test results on the producer’s website. Stay away from products that aren’t tested or have questionable test results, as you won’t know if they even contain delta-8, and they could potentially contain harmful substances.
 

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What is delta-10?





Delta-9 THC is the cannabinoid we all know and love—it’s the main compound in weed strains that gets people high and has been doing so for thousands of years. You may have heard of delta-8, which has gained in popularity in the past year or so, a cannabinoid similar to delta-9, but less potent.



Now, to confuse things even more, a cannabinoid called delta-10 is becoming more popular. Truly, it’s hard to keep up with weed trends.

So let’s see what the big deal is with delta-10, if it can get you high, how it compares to other cannabinoids, and how to get it.

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What is delta-10?
Delta-10 is a cannabinoid found in trace amounts in the cannabis plant. Like regular THC—delta-9—it can get you high, but it is less potent than delta-9. This makes it similar to delta-8, another cannabinoid that is less potent than regular THC.

According to Roger Brown, president and CEO of ACS Laboratory, a lab that tests hemp-derived products from 48 states, “Delta-8 was very popular and had really taken off, and now delta-10 has taken off as well, and we’re seeing it in a significant amount of products that are being tested.”

Delta-10 is commonly processed from hemp-derived CBD, as is delta-8. Because hemp is legal all over the US (more on that below), delta-10 is considered legal in all 50 states. However, as with delta-8, certain states have outlawed delta-10 on their own.

The cannabinoid is usually available in vape carts, gummies, or other edibles, and can be mailed to certain states.

What’s the difference between delta-8 and delta-10?
To create both versions of THC, CBD oil is first extracted from legally grown hemp. The resulting oil is processed into either delta-10 THC or delta-8 THC. Different chemicals and reactions are used to create the different deltas.

Delta-10 THC is not easy to manufacture. It must be refined extensively, so you usually don’t see it in abundance. “If you see a product out there that says 99% delta-10, I don’t believe it,” said Brown. Because it is so hard to produce, a lot of products combine delta-10 with delta-8.


Is delta-10 safe to consume?

Delta-10 is safe to consume, however, Brown stressed that as chemicals are used in the extraction process, it is critical to only consume delta products that have been lab-tested at an accredited lab to ensure they have been purged of all chemicals and contaminants and are safe for consumption.


Legitimate delta-10 products, like those tested at ACS Laboratory and other licensed labs, will have a QR code showing consumers the proof of testing certification.

What are the effects of delta-10?
Delta-10 can get you high, although it is much less potent than regular delta-9 THC. Anecdotally, delta-10 is commonly reported to provide energizing effects, whereas delta-8 is reported to be more sedating. Delta-10 is often compared to strains like Sour Diesel, Pineapple Express, or Super Lemon Haze, whereas delta-8 is compared to strains like OG Kush, Wedding Cake, and Purple Punch.

“To put it in perspective,” said Brown, “delta-8 is more like an indica and delta-10 is more like a sativa. They have two very different vibes to them. People who want to use a sleep aid, as an example, have used delta-8, [whereas] delta-10 gives you more creativity or perspective.”

It’s important to note that these effects are not based on any scientific study; more research is needed on these compounds. On top of that, every person has a unique body chemistry and compounds will affect people differently.


Is delta-10 legal?

Currently, delta-10 products are federally legal because they are derived from hemp, which was legalized in the US when Congress passed the 2018 farm bill. This is what makes delta-10 so appealing—consumers who live in states where cannabis is illegal can purchase delta-10 because it is technically derived from hemp and not cannabis. (Hemp is legally defined as a cannabis plant containing less than 0.3% delta-9 THC.) Although delta-10 is less potent than regular delta-9 THC, people can still get high from it, legally.

However, as is the case with delta-8, some states have taken it upon themselves to outlaw delta-10. Additionally, some delta-10 producers won’t ship to certain states if that state’s laws are unclear.

This leaves the legal landscape for cannabinoids messy. THC (delta-9) is recreationally legal in some states and medically legal in others. Delta-10 and delta-8 are illegal in certain states, but some of those states do have legal recreational or medical weed.

Be sure to check a specific producer’s website to see where they ship to, but by and large, if you live in these states, you cannot get delta-10:

  • Alaska
  • Arizona
  • Arkansas
  • Colorado
  • Delaware
  • Idaho
  • Iowa
  • Mississippi
  • Montana
  • Rhode Island
  • Utah
Whether delta-10 or delta-8 will get outlawed in more states is yet to be seen, but if that does happen, producers may move on to yet another new cannabinoid to skirt the law—maybe THC-O, maybe something else.

“If delta-8 is outlawed in states, they’re going to look for the next delta,” said Brown. “They’re just going to try and find a way around it.”
 

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Meet THC-O, a hemp-derived compound three times stronger than THC





In recent months, a synthetic compound derived from hemp called THC-O acetate—often referred to simply as THC-O (pronounced “THC oh”)—has quickly gained popularity among Americans who don’t have access to legal cannabis.


THC-O products are increasingly popular in states where consumers don’t have access to legal cannabis.
THC-O’s appeal lies in its potency and its legal status. Research has found that it’s roughly three times stronger than conventional THC. It has been called “the psychedelic cannabinoid” for its borderline hallucinatory effects. Because it’s derived from federally legal hemp, THC-O products are becoming increasingly popular in the states where consumers don’t have access to legal, state-licensed delta-9 THC products.

And now that delta-8 THC, its trendy cousin, has been outlawed in some states across the country and flagged by the DEA, THC-O’s star may rise even faster.

While THC-O products like vape carts and tinctures are available for purchase online, both their legal status and their safety remain unproven.

Read on to learn more about the history of THC-O acetate, its potential benefits, and the risks you should be aware of before trying it yourself.

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What is THC-O?
Although many of us only recently heard about THC-O, the US military began studying its effects as long ago as 1949; they observed it eroded dogs’ muscle coordination twice as much as conventional delta-9 THC.

Typically, acetic anhydride is added to delta-8 THC to produce delta-O acetate.
THC-O didn’t appear on the DEA’s radar until nearly 30 years later. In 1978, DEA agents discovered a clandestine lab in Jacksonville, Florida, had combined a cannabis extract with acetic anhydride. But over the following 10 years, THC-O did not enter the illicit market. Since it didn’t seem to be a growing problem, the federal drug agency declined further investigation into the unusual compound.

Today the production of THC-O acetate is raising concern among some in the state-licensed cannabis industry. To generate the molecule, a highly-flammable compound called acetic anhydride is added to THC molecules. The process involves a series of extractions that begin with hemp, the low-THC cannabis plant that was made federally legal by Congress in the 2018 farm bill. First, CBD is extracted from raw hemp. Then delta-8 THC is extracted from the CBD. Finally, acetic anhydride is added to the delta-8 THC molecules to make THC-O acetate.


Experts say this process should only be done under controlled laboratory conditions, due to the health risks involved.

More on hemp-based THC derivatives
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What is delta-8?

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You’ve heard about delta-8. Now, meet delta-10.

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Is delta-8 THC safe? Here’s what the experts say

Don’t make THC-O at home
“The process of making THC-O acetate is inherently dangerous,” the renowned cannabis researcher Dr. Ethan Russo recently told Hemp Grower. “This is something that’s got to be done in a technical lab with a vacuum hood [and] no exposure to humans.”

If you want to use delta-O, always buy, never DIY.
Some THC-O retailers have echoed Russo’s warnings on their own websites. “Please don’t try to make THC-O on your own,” cautions the Honest Marijuana Co., an online seller of THC-O products. “The process requires special equipment and advanced training to get right. And volatile, flammable, and explosive chemicals are necessary. It’s not worth your life (or your home or your eyebrows) to do something that a lab can do better and safer. If you want to use THC-O, always buy, never DIY.”

If produced successfully, THC-O acetate resembles a thick brown liquid, similar to motor oil. As such, it can be consumed in vape cartridges, tinctures, and edibles.

Is THC-O safe to consume?
A lack of research and a profound lack of regulation based on actual data means that mysteries about THC-O acetate are prevalent.


Beyond its potency, researchers have concluded that THC-O acetate is a “prodrug,” meaning that the compound is not activated until it has been metabolized. It takes about 20 to 30 minutes to kick in.

James Stephens is a cannabis researcher and chemist. He’s investigated the effects of THC-O as part of his work for Iron Light, a cannabis product and brand consultancy based in Missoula, Montana. Stephens cautions that there are wide variations in product quality right now, early in the compound’s commercial emergence.

“If you’re using low-quality extract material and low-quality reagents you bought online from Alibaba or whatever, you’re likely to get way less pure of a product than if you’re using clean [and pharmaceutical-grade] reagents and do a lot of downstream purification steps,” Stephens told Leafly.

Related
Is delta-8 THC safe? Here’s what the experts say

What’s in these products?

Stephens regularly reaches out to THC-O acetate producers online. When they send him testing results, he is alarmed by the lack of specificity. “It’s 10-15% unknowns in there. I ask, ‘What’s the rest of the stuff?’, and they say, ‘We don’t know’…That’s what usually shuts down the conversation.”

With any vape cartridge sold outside a state-licensed cannabis system, there’s always a concern about potentially toxic additives mixed into the cannabis oil. These thinning agents have caused serious health problems in the past, and there’s nothing to prevent unregulated companies from adding them without informing consumers.

Furthermore, Stephens noted that smoking the molecule in a vape cartridge invites another host of questions, since combustion can activate other chemical processes. “We just don’t know [what happens], but you can’t run around saying any of this stuff is safe,” he told Leafly.

It’s potent, so go slow
Stephens is likewise worried that adverse reactions to THC-O acetate could have larger repercussions for the legalization movement writ large. “My biggest fear,” he said, “is it just takes that first overdose to cause the equivalent of a satanic panic or whatever you want to call it.”

Overconsumption of traditional cannabis has never directly caused a death in humans. With a compound three times as potent as delta-9 THC, however, there’s a risk of consumers imbibing too much THC-O and suffering through some unpleasant effects. Of course, high-potency cannabis concentrates like dabbing oil, wax, and shatter have been legally sold for many years—so the risk of a bad trip with THC-O is all relative.

Is THC-O actually legal?
Well, it depends who you ask.

Producers of THC-O acetate products say they’re protected under the farm bill passed by Congress in 2018, because the molecule was derived from a chain of custody that began with federally legal hemp plants. But even they seem unsure. As Binoid, a top seller of the compound, as well as other derivatives like delta 10-THC and HHC, admits on the company’s own website, “That’s actually hard to say.”

As for their competitor Bearly Legal Hemp Company, their name says it all.

Some experts, however, believe the compound is not legal. They cite the 1986 Federal Analogue Act, which states that any substance analogous to a Schedule I drug—in this case, conventional THC—would itself qualify as a Schedule I drug.

But that argument could be similarly used to argue against the legality of delta-8 THC, or perhaps even CBD. It all depends on where the line between “analogous” and “non-analogous” is drawn.

State laws and regulations scrambling to catch up
As with products containing delta-8 THC and delta-10 THC, products with THC-O exist in the marginal legal space between hemp (which is legal nationwide) and cannabis (which is not). State regulators and legislators are currently playing whack-a-mole with the growing number of hemp-derived compounds, banning novel compounds only to see new derivatives take their place.

In legal adult-use states, cannabis regulators are by and large ignoring these hemp-derived compounds because they don’t fall under their strict regulatory purview. Local police and health authorities have more pressing matters, like violent crime and the coronavirus pandemic.

In the meantime, some state-licensed companies in legal states are becoming more concerned about unlicensed hemp-derived THC products undercutting their market and tarnishing the reputation of the cannabis sector with potentially unhealthy products.

Until THC-O and other hemp derivatives come under a state-regulated system, consumers will need to weigh the risks and benefits of these compounds for themselves.
 

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How to take THC-O—the right way




You’ve heard of delta-8 and delta-10, but THC-O is in a whole new league—and it’s just about to hit the mainstream. THC-O starts with a naturally occurring form of THC, but goes through synthesis in a lab to make something far more powerful than even standard THC.


This potent high can even be derived from hemp, so depending on where you live, you can likely get it in the mail instead of visiting a dispensary. That being said, there is still some debate about whether THC-O constitutes “synthetic THC” under federal law, which is still a controlled substance and illegal even when derived from hemp, so proceed with caution. Because it can only be made in a lab under very specific conditions, any THC-O product is only going to be as good as its manufacturer. But with established, reputable hemp companies like The Hemp Doctor entering the space, you don’t have to go too far to find something you can trust.



A THC-O high is a thrilling experience, but you’re probably not going to want to enjoy it when you have to get anything done, even if you normally smoke cannabis as a study buddy or to make doing dishes more interesting. Considering your setting is critical to having a good time, especially your first time trying it.

Courtesy of The Hemp Doctor
Here’s a little background on this cannabis craze—and how to set yourself up for success.

Manufacturers like The Hemp Doctor have perfected their extraction processes, so you’re going to get a higher-quality oil without hazardous by-products.
What exactly is THC-O?
THC-O’s full name is THC-O acetate, and when it’s made from hemp, it typically starts as a delta-8 extract. What makes it larger than life, and why it can only be made in a lab, is Acetic Anhydride. This chemical is highly corrosive and flammable, so don’t DIY this—having a house that’s not on fire is going to contribute to a better experience in both THC-O and life.


Besides, manufacturers like The Hemp Doctor have already perfected their extraction processes, so you’re going to get a higher-quality oil without hazardous by-products. Even more of a reason to leave it to the experts.

Once it becomes an acetate, THC gets a big boost in potency, with some even calling its effects psychedelic. The end product is a thick but viscous oil that can be prepared for eating or vaping.

What’s the right dose of THC-O?
The Hemp Doctor recommends starting slow, even if you have a high tolerance to other forms of THC: For a vape cart, take one short puff and wait at least 30 minutes before drawing again. In a high-quality cart like The Hemp Doctor’s THC-O Acetate Vape Cart Oil, the draw can be incredibly smooth, so make sure you’re not inadvertently dragging on it too hard!

Courtesy of The Hemp DoctorCreating the right THC-O experience
For the optimal THC-O experience, you’re going to want to set the mood—and that mood is not going to Six Flags and riding every rollercoaster. Try these ideas out instead.

Art party
Grab a few of your closest friends, pool all your art supplies, lay out a drop cloth, and take a small pull from an energizing THC-O strain like Trainwreck. Then, start creating—you could get weird with it or just draw little smiley faces depending on where the high takes you.

Beach blanket buds
If it’s a nice day out, plan a lowkey beach hang with snacks, plenty of drinking water, and a little shade. Don’t plan on swimming, just bask in the sea air and sunshine. A balanced hybrid THC-O strain like Runtz completes the picture.

Extra cozy movie night
Grab a few feel-good movies you haven’t seen in a while—perhaps a series of them—and stock up on plenty of microwavable popcorn, or whatever your preferred movie snack is. Cuddle up in a blanket, take a puff of a THC-O indica strain like Skywalker OG, and start your marathon. It’s OK to fall asleep in the theater when it’s your own couch.

Courtesy of The Hemp DoctorNature walk
Hiking is a tried-and-true stoner activity, but don’t push it your first time trying THC-O. Is there a park nearby with pretty sights and easy paths? A botanical garden? Somewhere with a lot of birds? Bring a water bottle, a friend, and an invigorating strain like Amnesia Haze.

Gorilla Glue game night
A game night is a low-pressure way to have some fun, whether you’re playing card games, board games, video games, or something else entirely. Will that hybrid THC-O strain add an extra challenge to a racing game—or will it make you weirdly unstoppable at charades?

Find these smokable THC-O strains from The Hemp Doctor and breathe easy knowing you’re getting only high-quality, thoroughly tested extracts.
 

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They pushing dat Delta hard in Gatlinburg, TN... 3 weekends ago while I was there, I saw it available IN MANY spots in a " tourist " town... But hemp IS legal here in TN
 

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Comparing THC compounds: What we know about THC-O versus delta-9 & delta-8!!!





THC-O acetate is even stronger than regular THC. Here’s what you need to know to try it safely.

From delta-8 to delta-10, cannabinoids from hemp are having a moment. And now there’s a new kid on the block poised for a takeover: THC-O. But while the deltas are gentler versions of the classic THC, or delta-9 of cannabis fame, THC-O can be three times stronger than its more mainstream cousin.


Because it’s made from hemp, THC-O occupies a different legal status than cannabis products, especially in many states that don’t have a recreational market yet. That being said, there is still some debate about whether THC-O constitutes “synthetic THC” under federal law, which is still a controlled substance and illegal even when derived from hemp, so proceed with caution.

There’s still a lot we’re learning about THC-O, although there’s research on it dating back as far as the 1940s. As its popularity rises, it’s critical to keep up with the facts—and how to find safe, effective, reputable products.



Here’s what we know about THC-O and how you can make sure it’s coming from a trusted source before you give it a try.

Courtesy of five™What is THC-O and where does it come from?
THC-O’s full name is THC-O acetate, and the earliest research we have on it dates back to American military experiments on non-lethal incapacitating agents in the 1940s. Researchers tested the compound on dogs. At the end of the experiment, the dogs had lost significant control of their motor function.


To derive THC-O from hemp, first CBD is converted to delta-8 or a similar THC modification. But it goes one step further. By adding Acetic Anhydride to the mix, it becomes an acetate—specifically, THC-O.



But don’t try this at home! Acetic Anhydride is highly corrosive and flammable, and puts your health, safety, and environment at risk unless it’s made in a highly-controlled lab environment. This is one of several reasons why you should only buy THC-O if you know it came from a reputable source.

How do you take THC-O?
Once finished, THC-O acetate is a kind of thick brown liquid. You can take it in a vape cartridge, a tincture, or an edible. It takes about 20-30 minutes to kick in.

Courtesy of five™What does THC-O feel like? How is it different from delta-8, -9, and -10?
Delta-8 and delta-10 are both milder, and generally less intoxicating, than traditional delta-9 THC. Delta-8 is known for more sedative effects, while delta-10 has a reputation for a more active, sativa-like high.


THC-O is significantly stronger than not only delta-8 and -10, but also regular THC. Some consumers have reported a more spiritual high with strong effects that can even border on hallucinogenic. Like any drug, effects and tolerance are going to vary from person to person.


How to buy THC-O safely

With THC-O largely unregulated, there are a lot of risks to buying THC-O from a mystery source. Cannabis researcher James Stephens told Leafly that sometimes producers don’t even know, or claim to not know, what’s in their own product: “I ask, ‘What’s the rest of the stuff?’, and they say, ‘We don’t know’…That’s what usually shuts down the conversation.”

There’s a possibility of toxic additives in THC-O oil, too—and we’ve already seen sketchy additives cause serious health problems. Because it’s so much stronger than other forms of THC, you’ll especially want an accurate potency.

You’ll want to buy from a company that’s completely transparent, with clear lab results and a high level of accountability to its customers. five has been making trusted, transparent, full-spectrum products that combine CBD with other beneficial hemp compounds for years, and they were one of the first companies to offer products containing delta-9 and delta-10. They know how to create perfect mixes of cannabinoids—and they’re experienced at making them safely, with the consumer’s experience in mind. They even offer certificates of analysis from third-party labs so you know that what it says on the bottle matches what’s inside the product.

Courtesy of five™
five has been hard at work developing THC-O products that meet their high standards. For now, you can get to know them through their fan-favorite offerings—and if THC-O appeals to you, you’ll know that you have a producer that you can trust for a great experience.

Right now, five is offering a special deal for Leafly readers. Hit the link below to try a full size product for free. You just pay shipping, and five covers the rest.

get free product
Daily Buzz Gummies: five’s flagship gummies are both delicious and powerful, with a full suite of beneficial plant compounds and 5mg delta-9 THC per gummy. Like all their gummies, they’re vegan, too. *Availability subject to local laws.

Sleep Gummies: five’s gummies for better rest add natural sleep aid melatonin to their perfect blend of hemp-derived cannabinoids—with up to six times the minor cannabinoids as other brands.

THC+CBD Liquid Capsules: Get all the benefits of full-spectrum hemp in an easy-to-use capsule packed with CBD, THC, CBN, and CBC.

Full Spectrum THC+CBD Chocolate: For a more luxurious edible experience, five offers their signature blend of cannabinoids in two flavors of chocolate: Milk Chocolate and Sea Salt Dark Chocolate.

Full Spectrum THC+CBD Oil: This is the oil that started it all. Two flavors of tinctures, citrus and mint chocolate, are packed with CBD, THC, CBN, CBC, and terpenes.
 

4 Dimensional

Rising Star
Platinum Member
I’ve been on it for over a year now.

delta-9 makes me anxious. I love the high I get from the traditional bud, but the anxious feeling the first hour can be a bit much, especially as I get older.

delta-8 is no where near as potent as d-9. However, I still get high and the high is very functional, so i get to have it at work or casual places where I’m not trying to look like I just smoked a pound. The anxious feeling is non-existent.

Now d-10. Again not as potent as d-9, but more potent than d-8. I got some d-10 that put me on my ass. It’s an indica and a version of granddaddy purp. It smokes great and it was grown locally. I don’t get the dry herb. I do gummies and vapes. I’m going to get some more today, but going for the sativa.
 

roots69

Support BGOL
Registered
I’ve been on it for over a year now.

delta-9 makes me anxious. I love the high I get from the traditional bud, but the anxious feeling the first hour can be a bit much, especially as I get older.

delta-8 is no where near as potent as d-9. However, I still get high and the high is very functional, so i get to have it at work or casual places where I’m not trying to look like I just smoked a pound. The anxious feeling is non-existent.

Now d-10. Again not as potent as d-9, but more potent than d-8. I got some d-10 that put me on my ass. It’s an indica and a version of granddaddy purp. It smokes great and it was grown locally. I don’t get the dry herb. I do gummies and vapes. I’m going to get some more today, but going for the sativa.

Right on and thanks for the feedback.. Let me ask you this, do you pick yours up at a smoke shop or corner store??
 

roots69

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Registered
What is HHC?


The hemp-derived cannabinoid has a lot of potential, but invites many questions, too
Among the wave of hemp-derived cannabinoids sweeping the country—delta 8 THC, delta-O THC, and delta-10 THC among them—few have eluded public understanding more than HHC. Googling the compound brings up a host of contradictory information: about its legality, its effects on the body, and even whether it occurs naturally in the cannabis plant.
Making sense of HHC is complicated in part because it has only recently reached the market and only a handful of retailers are selling it, mostly in the form of vape carts. The cannabinoid offers lots of potential, however; don’t be surprised if you start hearing more about it soon.

As state and federal agencies continue to ban delta-8 THC, the most popular hemp-derived cannabinoid, HHC offers a tiny bit more legal promise—and appeal—since it’s not actually a THC compound at all. It may also elude drug tests, although the evidence for that is purely anecdotal at this point.

“HHC is one of our fastest growing products,” Liam Burns, founder and CEO of Bearly Legal Hemp, one of the main retailers of the cannabinoid, told Leafly. “That’s due to regulations that have banned Delta-8, but people are buying it in states where they can buy Delta-8, too.”

Read on to learn more about HHC: how it’s made, its effects, its murky legality and what other questions remain.

What is HHC, anyway?
HHC was first created in 1944 by the American chemist Roger Adams, when he added hydrogen molecules to Delta-9 THC. This process, known as hydrogenation, converts THC to hexahydrocannabinol (HHC).


Hydrogenation isn’t limited to cannabinoid production. A similar process is used to convert vegetable oil to margarine.

While Adams created HHC from conventional cannabis-derived THC, these days the cannabinoid is typically derived through a process that begins with hemp, the low-THC cannabis plant that was made federally legal by Congress in the 2018 farm bill.

How is HHC made?
It’s a many-step process. First, CBD is extracted from raw hemp, distilled and isolated in a powder form. From there, things get a little more complicated.

Hemp-derived CBD acts as the base for the chemical reaction that creates HHC.
We spoke with Kyle Ray, chief operating officer of Colorado Chromatography, about the process his company uses. In addition to HHC, Colorado Chromatography also produces CBG, CBN, and other specialized compounds in its facility outside of Denver. (Bearly Legal is one of their clients.)

Ray described HHC manufacturing as a proprietary process that takes place inside a chemical reactor. “Think about the reactor as a black box,” Ray told Leafly. “In goes CBD, out comes HHC.”

Ray describes the HHC as a “gold dark oil that we refine from that stage” before distilling it.

Is it safe to make HHC?
Richard Sams, scientific director at KCA Laboratories in Nicholasville, Kentucky, has tested HHC products in the past few months (including, incidentally, Bearly Legal’s). He told Leafly HHC can be produced safely in a well-equipped laboratory. But if you scale up production, he said, the risks rise, too. “The potential risk here is with explosions,” he explained.

Kyle Ray, of Colorado Chromatography, noted the company only makes its HHC in an “explosion-proof” space. “Everything’s grounded,” he said. “There’s no potential for static discharge.”

What are the effects of HHC on the body and mind?
There is a lack of consensus around HHC’s potency. The complication arises, in part, from the fact that when the cannabinoid is manufactured, the end result is a mixture of two different kinds of HHC molecules: 9R HHC actively binds to the body’s natural endocannabinoid receptors, while 9S HHC, because of its slightly different molecular structure, doesn’t do so nearly as well.


“The one that fits [into the receptors] produces similar effects” as delta-8 THC, but takes a much higher amount to do so, said Richard Sams of KCA Laboratories. “With a sufficient dose, THC-like effects can be observed.”

In other words, HHC can have THC-like effects on the body and mind, but HHC is less potent, milligram-per-milligram, than delta-8 THC. Delta-8 THC is itself generally regarded as about half as potent as the standard delta-9 THC.

How potent is HHC?
Kyle Ray, of Colorado Chromatography, told Leafly that while the ratios of the active and inactive HHC molecules can vary from batch to batch, they need to be at least 50% active to pass muster.

I tried it: HHC offered a pleasant and mildly cerebral high, with some pain relief.
“Trying to get those two isolated and separated from each other would be so cost-ineffective that it wouldn’t really make a viable product,” he explained. “So our goal, when we’re making our HHC, is always to maximize the amount of the active [compound] and minimize the amount of the less active [compound]. However, it’s never a perfect gambit. It’s usually somewhere around 2:1 or 1:1.”

When it comes to the effects of HHC, Liam Burns, of Bearly Legal, is a true believer.

“Personally, with HHC, I feel energetic,” he said. “I go to the gym. I’m sharp, my brain’s working properly. I typically have back and shoulder pain, but I have no pain when I’m on it.”

Aside from a faintly plastic-y taste, my own experience with the company’s HHC vape carts was similarly pleasant. Although the Blue Dream cart didn’t give me the same energy boost, it offered a pleasant and mildly cerebral high, and it did in fact soothe my aching muscles, too.

Does HHC show up on a drug test?
Burns, of Bearly Legal, believes that some of HHC’s appeal stems from evidence suggesting that it can evade drug tests. But—and this is important—he acknowledges the evidence is only anecdotal. This is just what he’s hearing from his customers.

James Stephens, vice-president of innovation at Creo, a biotech firm specializing in cannabinoids, has seen similar arguments made about HHC. “I’ve also seen it advertised that [HHC] doesn’t convert into 11-hydroxy-THC, which is a common drug test metabolite,” he told Leafly. “It could possibly be used to evade drug testing regimes if this proves to be true,” he added.

Word to the wise: There is no hard evidence that HHC does not show up on a drug test for marijuana. Don’t bet your job or career on anecdotal evidence.

Is HHC safe to consume?
Like any of the new hemp-derived cannabinoids, there is no standard dose and little to no research on the immediate or long-term effects of HHC ingestion.

Because hemp-derived cannabinoids (including HHC) are not subject to cannabis regulations in legal adult-use states, HHC product makers and retailers are not required to test their products for potency and purity.

Bearly Legal, however, does include third-party testing results with their HHC products, from KCA Laboratories. Those tests show the vape carts to contain about 99% HHC. (The ratio of 9R and 9S HHC molecules in the test added up, strangely, to a tad more than 100%. Colorado Chromatography attributed that to slight deviations within the margin of error).

Binoid, another major retailer of HHC, did not respond to multiple requests for comment for this story.

Is HHC legal?
And now we arrive at perhaps the thorniest question of all: Is HHC legal?

Bearly Legal says yes. The company’s website argues that since HHC is hemp-derived, and not actually THC, they should be in the clear. “HHC vapes, gummies, or edibles are perfectly legal on the federal level and will most likely remain legal on the state level as well,” the website reads.

Company officials additionally argue that since HHC is found in the seeds and pollen of hemp plants, it is “non-synthetic” and thus a “perfectly federally legal hemp extraction.”

Other retailers, unsurprisingly, agree. In a strange piece of branded content that recently ran in LA Weekly, Binoid claimed that the cannabinoid is legal…with the caveat that it “may possibly” be shipped to all 50 states.

Other experts are more skeptical. James Stephens, the cannabinoids scientist at Creo, believes HHC is subject to the Federal Analogue Act, which states that any substance analogous to a Schedule I drug—in this case, conventional THC—would itself qualify as a Schedule I drug. Since THC remains illegal, HHC would be illegal too. Stephens also believes it bears significant similarities to the synthetic drugs K2 and Spice, which mimic THC and are also classified as Schedule 1 drugs.

“I don’t think HHC is legal,” he told Leafly.

For the moment, HHC products exist (and thrive) in the murky legal zone between hemp (which is legal nationwide) and cannabis (which is not). Until HHC comes under a state-regulated system, consumers will need to weigh the risks and benefits of these compounds for themselves.
 

DJCandle

Well-Known Member
BGOL Investor
I get mine at a local CBD store. It’s homegrown stuff, so very authentic. I don’t mess with the corner stores. NC got a ton of legit hemp spots all over.
I’ve actually fallen back from dispensaries and commercially available herb for a year or two now. I personally LOVE smoking homegrown and prefer it to all the wacky strains out there. There’s no substitute for that authentic taste flavor and high.

Homegrown delta-8 is the smoothest thing you can find right now. :yes:
 

4 Dimensional

Rising Star
Platinum Member
I’ve actually fallen back from dispensaries and commercially available herb for a year or two now. I personally LOVE smoking homegrown and prefer it to all the wacky strains out there. There’s no substitute for that authentic taste flavor and high.

Homegrown delta-8 is the smoothest thing you can find right now. :yes:

I tried the dry herb delta-8 once it was a total waste of money. I messed around with a few vapes until I found one that didn’t burn my throat at all. Some of those vapes are too harsh. But the homegrown stuff is super smooth.
 

roots69

Support BGOL
Registered
I’ve been on it for over a year now.

delta-9 makes me anxious. I love the high I get from the traditional bud, but the anxious feeling the first hour can be a bit much, especially as I get older.

delta-8 is no where near as potent as d-9. However, I still get high and the high is very functional, so i get to have it at work or casual places where I’m not trying to look like I just smoked a pound. The anxious feeling is non-existent.

Now d-10. Again not as potent as d-9, but more potent than d-8. I got some d-10 that put me on my ass. It’s an indica and a version of granddaddy purp. It smokes great and it was grown locally. I don’t get the dry herb. I do gummies and vapes. I’m going to get some more today, but going for the sativa.

Bruh, one more question?? Are these D's made in tinctures, I see u said they got edibles?? Im going to venture out today and see where I can find sum..
 

4 Dimensional

Rising Star
Platinum Member
Bruh, one more question?? Are these D's made in tinctures, I see u said they got edibles?? Im going to venture out today and see where I can find sum..

Yes. Very concentrated stuff. I never bought any, but you can get d8 in tinctures.

They also as distillate for making your own edibles. You can put it one any food source.
 

Darkness's

" Jackie Reinhart is a lady.."
Registered
Delta 8 is bullshit. There are mom and lol convenient stores that sell pre stuffed cones and intried them. A waste of money.
 

cashwhisperer

My favorite key is E♭
BGOL Investor
Delta 8 is bullshit. There are mom and lol convenient stores that sell pre stuffed cones and intried them. A waste of money.

I've had potent Delta 8. It's pretty good. These gummies and vapes be on that bullshit. I got the actual dry herb. Not bad at all for what it is.
 

Sloboogie

Rising Star
BGOL Investor
Delta 8,9,10... none of that matters if we're not talking about the mg dosage. I've had some Delta 9 25mg that gave me a potent high. I've also had some Delta 8 at 45mg that had me high for almost 2 days. I gotta cut that shit up in quarters....
 
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